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Imagine that a pharmaceutical company, specifically the research and development division, just hired you. Your first assignment consists of developing a new anticancer drug to control the high rates of glycolysis in tumor cells. Your company wants to target an enzyme different to hexokinase II, because they want to get […]

You characterize a new enzyme’s kinetics. Using a saturating (very high so all E is ES) substrate concentration, you measure the initial rate of the reaction at various enzyme concentrations. Does this data fit the Michaelis Menton model/equation? If not, what may be happening? E (nM), rate (mM,s) 5, 5010, […]

In a series of experiments, genes that code for mutant forms of a receptor tyrosine kinase are introduced into cells. The cells also express their own normal form of the receptor from their normal gene, although the mutant genes are constructed so that they are expressed at considerably higher concentrations […]

1. The net effect of the effector is to shut off the original ________, or reduce its intensity, during the negative feedback mechanism to restore homeostasis. a. response b. receptor c. control center d. stimulus 2. When we imagine a person exhibiting anatomical position, the palms of the hands are […]