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Human populations are known to isolate themselves from other groups based on cultural identity, language religion, etc. Some of these communities in North America include the Ashkenazi (descendants of European Jewish communities, Yiddish speakers), the Cajun population of Louisiana, the Arcadian population of Canada, and the Old Order Amish community […]

1) Represent graphically the relation between melting temperature and the G-C content of DNA. a) Construct relations for dependence of melting temperature of a 30 bp DNA duplex on the G-C content. For series of the DNA chains where we vary the number of G-C pairs, plot how Tm changes […]

Question: Two protein kinases, PK1 and PK2, work sequentially in an intracellular signaling pathway. You create cells that contain inactivating mutations in the genes that encode either PK1 or PK2 and find that these cells no longer respond to a particular extracellular signal. You also create cells containing a version of […]

Suppose that pattern baldness is caused by a single autosomal gene mutation that has a dominant effect in males (either one or two copies of the mutation cause pattern baldness) and recessive effect in females (two copies of the mutation cause pattern baldness). A second gene on a different autosomal […]