Microtubule system is dramatically reorganized when an interphase cell enters mitosis. In order to investigate the mechanisms of this transition, you compare the microtubule dynamics in interphase and mitotic cells. You have cells expressing fluorescently labeled tubulin to do your assays, as well as all necessary equipment. 5.1. As a […]

1:What types of evidence indicate that cancer arises from genetic changes?2: Discuss how is cancer different from most other types of genetic diseases?3:Outline Knudson’s multistage theory of cancer and describe how it helps to explain unilateral and bilateral cases of retinoblastoma.4:What is haploinsufficiency? How might it affect cancer risk?5:What role […]

In cats, coat color is an X-linked trait where a black coat is determined by the XB allele and a yellow coat by the Xb allele. Black and yellow are co-dominant and a heterozygote has a tortoiseshell coat.a) A yellow female cat is bred to a black tom. Write out […]

Assume you have discovered a new Xenopus gene that codes for a RNA binding protein. You are not sure what its function is but you are interested in finding out as much as you can about the protein’s role in development of the embryo (from oocyte to tailbud stage) so […]