A 30 kg cocker spaniel is admitted to the hospital for exercise intolerance secondary to heart failure. You perform renal function measurements after infusing para-amino hippuric acid (PAH) and get the following values:Plasma creatine = 0.02 mg/ml (2mg/dl)Urinary creatine = 1.25 mg/mlUrinary volume = 30 ml urine in 60 minutesPlasma […]

1. How many total base pairs are in all the mammalian genes? 2. What proportion (%) of the total genome does this represent? 3. What is the probability that a random mutation will occur in any given gene? 4. Only 1 out of 3 mutations that occur in a gene […]

1. Bacteriophage M13 infects E. coli differently from the way bacteriophage T2 does. The M13 coat is removed in the inner membrane of the bacterial cell, where it is sequestered during phage replication. It is subsequently used to package the newly replicated phage DNA to create progeny phage. Why would […]

Q1. Suppose that the allele controlling brown eyes (B) is dominant over those controlling blue eyes (b) in human beings. (In actuality, eye colour in humans is an example of multigene inheritance, which is much more complex than this.) A blue-eyed man marries a brown-eyed woman; and they have six […]