1. How many total base pairs are in all the mammalian genes? 2. What proportion (%) of the total genome does this represent? 3. What is the probability that a random mutation will occur in any given gene? 4. Only 1 out of 3 mutations that occur in a gene […]

Q1. Drug effects are conditional. Drugs can target redundant gene products not limited to model systems Active compounds can help define drug leads and new “druggable” targets. Target identification can be technically challenging probably not as random as mutagenesis. What is essential for effective chemical genetics? Q2. Describe the term […]

The coat color in mink is controlled by two codominant alleles at a single locus. Red coat color is produced by the genotype R1R1, silver coat by the genotype R1R2, and platinum color by R2R2. White spotting of the coat is a recessive trait found with the genotype ss. Solid […]

Part 1. Google “Transforming a Clinician Into an Investigator”.  Click on the top Medscape.org hit.  Watch the FDA panel discussion (maybe slow to load, and you may have to create an account) and answer the questions below in your own words, together with your thoughts on the topic discussed. Discuss […]