What types of matings would lead to elimination

How many hemoglobin molecules are there in a red cell
April 15, 2020
If long radishes are crossed with oval radishes
April 15, 2020

What types of matings would lead to elimination

A man has fragile X syndrome. What is his genome like (regarding his sex chromosomes)? If he has a child with a normal woman, what are the chances of the child’s having fragile X syndrome if it is a boy? If it is a girl? What are the possible pedigree outcomes for future generations? What types of matings would lead to elimination of this disease from the future family lineage? Could such a condition suddenly appear in a family lineage? If so, how?