What mutation could invert the topology totype III
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April 19, 2020What is the meaning of human history
April 20, 2020What mutation could invert the topology totype III
A protein is inserted in the ER membrane with type II topology (N -terminus in cytosol). What mutation could invert the topology totype III (C-terminus in cytosol)?
a) The positively charged residues N-terminal of the Signal Anchorsequence need to be mutated and positively charged residues C-terminal of the Signal Anchorsequence need to be added.
b) The positively charged residues N-terminal of the Signal Anchorsequence need to be mutated.
c) positively charged residues C-terminal of the Signal Anchorsequence need to be mutated.
d) None of the above.
