What is the probability that an affected offspring

The answers to the given question are already provided, but could someone please explain how this was derived. Thank you! In a particular population of humans that has presumably reached Hardy-Weinberg equilibrium, the frequency of alkaptonuria, caused by homozygosity for a recessive gene, is one per million. What is the probability that an affected offspring will be produced by: (a) A mating between two normal nonrelated individuals? (b) a mating between a person who has alkaptonuria and a normal nonrelated individual? (c) a mating between a normal individual with normal parents, who has an alkaptonuric brother, and a normal nonrelated individual? a. 1 X 10-6 b. .001 c. 3.35 X 10-4

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