At puberty, an adolescent female body changes in both structure and function of several organ systems, primarily underthe influence of changing concentrations of estrogens and othersteroid hormones. How can one hormone, such as estrogen, mediate somany effects?

A) Estrogen is produced in very large concentration and thereforediffuses widely.

B) Estrogen has specific receptors inside several cell types, buteach cell responds in the same way to its binding.

C) Estrogen is kept away from the surface of any cells not able tobind it at the surface.

D) Estrogen binds to specific receptors inside many kinds of cells,each of which have different responses to its binding.

E) Estrogen has different shaped receptors for each of several celltypes.