Write a Brief report on the topic :”Protein Phosphatase”

Introduction:-Protein phosphorylation constitutes to one of the major types of reversible post transnational modifications that can regulate the stability, localisation or the function of a particular protein. Hydroxyl group containing amino acids such as Ser, Thr & Tyr are the sites of phosphorylation in proteins (approximately 86%, 12% and 8% of the phosphoproteome respectively). Phosphorylation at these amino acid residues is catalysed by a specific group of enzymes known as “PROTEIN KINASES”.

Address the following points given below:

• Introduction
• Classification of protein phosphates
• Structure and mechanism of action
• Physiological significance of phosphate function
• Laboratory methods to study protein phosphorylation/dephosphorylation
• Disease relevance and therapeutic significance
• Obstacles in analysing phosphate function 
• Future directions
• References

Academic requirements:

• Your work must be submitted as  2600 words.

• Your work should be submitted in the formats outlined for each point in the assignment

• The entire assignment brief and completed .

• All work must be referenced using the Harvard /APA method.

• Provide a reference list