Solution-Mutation on the transcription at the locations

A promoter is a DNA sequence that is upstream of a gene. Promoters comprise about 35 base pair consensus sequences that are required for transcription initiation. The figure from the textbook shows the positions of the consensus sequences in a promoter:

Predict and explain the possible effect of a mutation on the transcription at the following locations:

  • -7
  • -19
  • -32
  • +1

 

Solution

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