Solution-How does the acetyl-coa move from the matrix to

In mammalian cells, fatty acid synthesis occurs in the cytosol. The beginning substrate for this series of reactions is acetyl-CoA, which is formed in the mitochonrdrial matrix. How does the acetyl-CoA move from the matrix to the cytosol?

a.Acetyl-CoA reacts with oxaloacetate and leaves the matrix as citrate via the citrate transporter.

b.Acetyl-CoA combines with bicarbonate and is transported out of the matrix as pyruvate.

c.There is a specific transport protein for acetyl-CoA.

d.Acetyl-CoA is a non-polar molecule that can diffuse across all membranes.

e.Inner and outer mitochondrial membranes are freely permeable to acetyl-CoA due to the presence of transmembrane pores.

Solution

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