1. Briefly present the most common side effects of cardiovascular drugs. Why some of them can cause electrolyte abnormalities, dysrhythmias or drug-drug interactions. Give some examples.

2. Present the rationale for clinical applications of renin-angiotensin inhibitors. What are the major side effects?

3. What is a difference between centrally acting sympatholytics and peripherally acting sympatholytics? How can they be used in clinical practice?

4. Describe the mechanism of action of diuretics. Give a comparison of their pharmacokinetic parameters and site effects.

5. Describe the mechanism of action of antiarrhythmics. Give a comparison of their electrophysiological actions, clinical applications, drug-drug interactions and their site effects.