Mutation resulting from lack of a mismatch-repairsystem

MC4100 mutS cells are spread onto a single LA/?vir plateand incubated overnight at 37° C. The next day there aremultiple bacterial colonies growing on the plate. Decide whethereach of the following (A-C) could account for the bacterialresistance to ?vir:

I. This could account for the bacterial resistance to?vir.

II. This could NOT account for the bacterial resistance to?vir.

C. A mutation in malK

B. A spontaneous mutation resulting from lack of a mismatch-repairsystem

A. A mutation preventing ?vir from entering the bacterial cell 

Solution

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