Lysozyme has two key catalytic residues, Glu35 with a pKa of 5.9 and Asp52 with a pKa of 4.5. If the pH optimum for this enzyme is 5.0, what does this tell you about the mechanism?

a. Asp 52 is more likely a nucleophile than Glu 35.

b. Glu 35 is more likely a general acid than Asp 52.

c. Both of these are true.

d. Neither of these are true.