Two dissimilar inbred strains of mice, A and B, are crossed to yield an F1 hybrid strain, AB. If a large dose of spleen cells from an adult A mouse is injected into an adult AB mouse, which one of the following is MOST likely to occur?

A. The spleen cells will be destroyed.

B. The spleen cells will survive and will have no effect in the recipient.

C. The spleen cells will induce a graft-versus-host reaction in the recipient.

D. The spleen cells will survive and induce tolerance of strain A grafts in the recipient.