How will mutation affect relation in reaction nd concentrion

Two hybrid system to detect interactions between proteins
April 13, 2020
Value of the transmembrane voltage
April 13, 2020

How will mutation affect relation in reaction nd concentrion

An enzyme that follows the MWC (also known as the concerted model) model for allostery has a T/R ratio of 300 in the absence of substrate. Suppose that a mutation were to reverse that ratio(T/R= 1/300= 3.3 x 10^-3). How would this mutation affect the relation between the rate of the reaction and the substrate concentration, i.e. what would the initial velocity vs. [S] plot look like and why?