How many replicons would be there per chromosome

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April 30, 2020
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April 30, 2020

How many replicons would be there per chromosome

Human genome has 3×109 (3 billion) base pairs in a haploidgenome. The part of the cell cycle where DNA synthesis occurs (S-period) is 9 hours long. Assuming that therate of fork movement in humans is 20 bp/sec, estimate the number of replicons (replicating units;origins of replication) in the whole genome? Assuming equal amount of DNA in every human chromosome,approximately how many replicons would be there per chromosome?