How many errors would you expect in the replication

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April 5, 2020
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April 5, 2020

How many errors would you expect in the replication

Suppose a primer initiates the replication process in E. Coli and forms a 20bp (base pair) long stretch. Assume an error rate of 2/1000bp in primer that is taking place only in the lagging strand of DNA during replication. How many errors would you expect in the replication of 3800000bp long genome of E. Coli considering Okazaki fragments are 2000bp long and are primed with primer which is not removed from the replicated strand?