You have to answer some questions based on 3 articles ( you will find the articles in the attachment ) ..

Questions :

A. What is the PPAARE question for each of these articles? Create a table to show the different parts.

B. In the TREATMENT article, what kind of study was conducted? How was efficacy measured? How was safety measured? What dosages were tested? Was adherence determined? How? How would you explain the findings of this study to a patient?

C. In the HARM article, what type of study was conducted? How was harm reported? Were there potentially confounding factors? How would you explain the results of this study to a pregnant patient taking an SSRI?

D. In the PREVENTION article, what type of study was conducted? What was the main outcome measure? What was the Absolute Risk Reduction (ARR) in patients taking risedronate vs. placebo and the Number Needed to Treat (NNT) with risedronate to prevent hip fracture? What does NNT mean?

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E. How were these studies similar? How were they different? Which one was the most difficult for you to make sense of? Why do you think that was?