Fuse cells using polyethelyne glycol

If you fuse cells using PEG (polyethelyne glycol). The resulting cell generally retains two nuclei and the associated endomembrane system proximal to that nucleus. However, the plasma membranes of the cells mix. When a retinal cell is fused with a pancreatic cell the following might happen:

a) The cell no longer makes opsin. Explain.
b) The cell no longer produces insulin. Explain.
c) The nucleus derived from the retinal cell is producing mRNA for insulin. Explain.

d) The nucleus derived from the pancreatic cell produces mRNA for opsin. Explain.

Solution

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