Develop suitable rate expressions for product formation

Develop suitable rate expressions for product formation

Consider the following reaction sequence S + E <–> (ES)1 <–> (ES)2 –> P + E The first reversible reaction has forward and reverse rate constants of k1 and k2; the second reversible reaction has forward and reverse rate constants of k3 and k4; the third irreversible reaction has a forward rate constant of k5. Develop suitable rate expressions for product formation [=k5(ES)2] using the (a) rapid equilibrium approach and (b) quasi steady state approach.

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