Determine the frequency of mutant allele in the population
What laws and concepts are covered
April 23, 2020Explain a type of column chromatography
April 23, 2020Determine the frequency of mutant allele in the population
Imagine a population of 12,000 people: 7,000 females and 5,000 males. Syndrome A is an Xlinked recessive disorder. The population contains 134 affected females, 1682 carrier females and 710 affected males.
3A. What is the frequency of the normal allele in the population?
3B. What is the frequency of the mutant allele in the population?
3C. Without doing a formal Chi square test, compare your observed genotype frequencies with
those you would expect from HWE theory. Does the population appear to be in HWE?
