Describe the consequences of each of the following mutations in glycogen metabolism (name the pathways affected and specific effects on them e.g. , compounds/molecules that don’t form or accumulate as a result, change in structure of glycogen, reduced activity)

a. Loss of the AMP-binding site in muscle phosphorylase

b. Loss of the phosphorylase kinase gene

c. Loss of the gene that encodes inhibitor 1 of protein phosphatase I

d. Loss of the gene that encodes glycogenin