The symptoms that Mrs. Lakin presents with can be treated with a neuraminidase inhibitor. She should be given a full dose of Oseltamivir.

2. Pharmacokinetics, pharmacodynamics, and parmacotherapeutics:
3. Oseltamivir

Action: The drug acts by inhibiting the influenza neuraminidase enzymes. These enzymes are responsible for the replication of the virus. Their inhibition prevents further spread of the   virus to the other areas of the body.

Uses: Oseltamivir is used to treat influenza in children who are equal to or more than one year of   age and adults of all ages. It is also used to prevent flu during flu outbreaks.

Contraindications of Oseltamivir: it is not indicated for children less than one year, patients with   kidney problems, confused patients, patients with delirium, and patients with suicidal   thoughts (Wynne & Woo, 2002).

Drug-drug reactions: the drug doesn’t have significant drug interactions, an advantage of its use of esterase enzymes.

Drug-food interaction: when Oseltamvir is administered with food, absorption of the drug is not   affected, only the time to its maximum concentration is limited.

Adverse effects: patients report nausea, diarrhea, vomiting, stomach pain and headache

Patient teaching:The patient is advised to adhere to the dose, and to monitor any adverse side effect like rash.

1. Amantadine

Action:in the treatment for Parkinsonism using amantadine, the drug has three mechanisms of   action. It activates the production and increases it, it deactivates the production of   acetylcholine and decreases it, and it blocks the sites where glutamate acts, reducing its action.

Uses: amantadine is used in the treatment of Parkinson disease, herpes zoster, and influenza.

Contraindications: it is contraindicated in closed angle glaucoma, epileptic seizures, blood pressure that drops on standing, patients with suicidal thoughts, chronic heart failure, malignant tumor, and in visible water retention.

Drug-drug interactions: there are several drugs known to interact with Amantadine. Some of them are acetaminophen, bupropion, tramadol, and iopamidol. The drug has three categories of drug interactions. These are, six major drug interactions, three hundred and fifty moderate, and sixty two minor interactions.

Food-drug interactions: amantadine has not been found to cause drug interactions with food when taken with food.

Adverse effects: these include blurred vision, confusion may occur, the user may have difficulty urinating, swelling in the extremities and hallucinations (Wynne & Woo, 2002).

Patient teaching: the patient is taught about the dosage and the disease that is being treated. They are also taught about the side effects of the drug, and encouraged to report any abnormal signs immediately.

3. Patient teaching that will be provided:

Mrs. Lakin will be taught about her disease and the best medications she will be given, in this case, Oseltamivir. She will be taught about the mode of action of the medication, and the dosage, as well as, the side effects. She will be emphasized about the serious adverse effects of the drug, and taught o how to recognize them, and advised to report any abnormal sign immediately. Further, she will be taught about the importance of adhering to the prescription.

4. To prevent other people from getting the flu, Mrs. Lakin is nursed through barrier nursing. She is isolated from the other patients. She is also taught on the importance of preventing transmission to other people. The nurse attending her protects themselves by use of masks and gowns.
5. The effect of the virus in Mrs. Lakin’s body is to weaken the immune system. To prevent infection from opportunistic bacteria, the patient is given prophylaxis with an antibacterial like amoxicillin.

Reference

Wynne, L.A., & Woo, M.T. (2002). Pharmacokinetics for nurse practitioner prescribers. Philadelphia, PA: F A Davis Company.