Question: A certain allele of the ApoE gene in humans has been linked to an increase in susceptibility to Alzheimer’s disease, which causes dementia. Assuming there is no human interference, would you expect the frequency of this allele in the population to change over time? If so, would the frequency increase or decrease? Explain.

Question: What is the advantage for higher eukaryotes to include introns within their pre-mRNA transcripts?