Xeroderma pigmentosum, The condition “xeroderma

The condition “xeroderma pigmentosum” is characterized by high rates of skin cancers like malignant melanoma. It is caused by mutations in any of several genes that encode enzymes that participate in:

   
   
   
    disruption of base-pairing of the DNA in the area around a thymine dimer.
Replication protein A (RPA):

   
   
   
   

 

 

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