Solution-Why is this a life-threatening emergency

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Solution-Why is this a life-threatening emergency

Please respond to the following questions.

These are also found in the “For Further Thought” sections of your textbook.

1. The success of an organ transplant depends on many factors. What unavoidable factor would diminish the chance of success of a lung transplant, but is not a factor at all in a heart transplant?

2. At a construction site, a hole caved in and buried a workman up to his shoulders in wet sand.

The foreman told the trapped man that a crane would be there in 20 minutes to pull him out, but another worker said they couldn’t wait, and had to dig NOW. He was right. Why is this a life-threatening emergency?

Answered:-

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The lung allograft communicates directly with the outside environment. So, whatever is inhaled is in direct contact with the transplanted lung. It is very well understood, that the inhaled gas may contain infectious substances like bacteria, virus etc.

Now, if a person having lung transplant, inhales some infectious agent, then that infectious agent will come into the transplanted lung. Since, this lung is foreign, so, the infectious agent is completely new to the body of this patient.

And the body does not have enough immune response (cellular and humoral immunity) to cope up with this foreign infectious agent. So, immune system gets a signal that some totally new substances are there in the body; this starts production of immune cells; antibodies/complement/cellular immunity; in to the body, to cope up with totally new agents.