1. Imagine a population of 10,000 humans living on an isolated island. Every generation, an average of one individual is born with cystic fibrosis, a fatal genetic disease caused by a recessive allele (ie., individuals with the condition are cc, Cc individuals are unaffected, but carry the allele)

1. What are the frequencies of the dominant, and recessive alleles?

2. What proportion of the population are carriers?

3. What is the selection coefficient against individuals with the disease?