1.
A drug impairs oxyegen consumption on liver mitochondria at a buffer of 7.4pH, Mg, and adp. It inhibits O2 uptake if isocitrate, 2-ketoglutarate and malate were substrates, but it will NOT is succinate is a substrate.

Where’s the site of inhibiiton: ATP synthase, malate dehydrogenase, Complex I, II, or III

2.
What is the compound that’s the oxidizing agent for Complex II of the respiratory chain?

3.
What is the enzyme of beta-oxidation that’s analoguos to malate dehydrogenase RXN?