1) Consider that, in the hypothetical study given in the table below, cases underestimated their exposure and, as a result, 20% of exposed cases were falsely classified as unexposed, however that the classification of controls was not affected.
True results of the hypothetical case-control study with no measurement error.
|
Cases |
Controls |
Total |
Exposed |
300 |
250 |
550 |
Unexposed |
100 |
150 |
250 |
Total |
400 |
400 |
800 |
Explain whether this kind of the misclassification is random or systematic? Specify is it differential or non-differential?
b) Specify the effect it would have on the results of study?