Recognizing hypothetical case-control study

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Recognizing hypothetical case-control study


1) Consider that, in the hypothetical study given in the table below, cases underestimated their exposure and, as a result, 20% of exposed cases were falsely classified as unexposed, however that the classification of controls was not affected.

True results of the hypothetical case-control study with no measurement error.

 

Cases

Controls

Total

Exposed

300

250

550

Unexposed

100

150

250

Total

400

400

800

Explain whether this kind of the misclassification is random or systematic? Specify is it differential or non-differential?

b) Specify the effect it would have on the results of study?