1. Given a protein as a potential antigen specific to a viral infection, what assay would best identify titers in the patients to indicate exposure and immune response?

2. If the classical or alternate complement pathways were activated in response to the Middle Eastern respiratory syndrome coronavirus (MERS-CoV), discuss which complement products would most likely contribute to innate and adaptive immunity.

3. Performing a bronchial lavage from a patient infected with MERS-CoV, what assay and what reagents would identify whether macrophages could contain the virus?