Hereditary fructose interolance

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Hereditary fructose interolance

Question:  Hereditary fructose interolance is a rare recessive disorder that is caused by a mutation in the aldolase B gene. As a result of this disorder individuals may have all of the following symptoms except:
-inability to metabolize lactose
-reduced blood sugar during fasting
-reducing sugar in urine

Question:  Under fasting conditions, individuals with a deficiency in hepatic glucose 6 phosphatase can not dephosphorylate glucose 6 phosphate generated from liver glycogenolysis. As a result of this disorder, which of the following is most likely to occur in this individual when the ratio of insulin to glucagon is low?
-hyperglycemia
-increase skeletal muscle glycogenlysis
-no impact
-increased glucose output from liver

Question:  Certain conditions such as excessive alcohol consumption can increase the ratio of NADH/NAD+ in the mitochondria. This will directly inhibit which of the following enzymes?
-citrate synthase
-pyruvate dehydrogenase
-isocitrate