Genetic mapping of alkaptonuria

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Genetic mapping of alkaptonuria

Question: The OMIM description on “Genetic Mapping of Alkaptonuria” can be interpreted to say: The alkaptonuria gene was genetically mapped to 3q2 at 16cM away from the sucrase-isomaltast deficiency gene in inbred families with some members manifesting both conditions. Statistically the alkaptonuria causing mutant gene and the sucrase-isomaltase deficiency-causing mutant gene appear on the same homologous chromosome in approimately ____% of all Chromosome 3’s evaluated in the inbred-family studies that mpped out the 16cM distance between the two genetic loci.