Estimation of expected phenotypic ratio of offpsring

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Estimation of expected phenotypic ratio of offpsring

Question: For the fish model organism Medaka (Aplocheilus latipes), genes at 2 loci (B, b and R, r) determine color of the fish. Fish that have the dominant allele at both loci (B_ R_) are brown, fish with a dominant allele at the B locus (B_) are blue, fish with a dominant allele at the R locus only (bb R_) are red, and fish that are homozygous recessive at both loci (bb rr) are white.
a. What is the expected phenotypic ratio of offpsring of cross betweena homozygous brown and homozygous white Medaka fish?
b. What is the expected phenotypic ratio of offpsring if you then generate an F2 generations from the progeny above?
c. Assume that you performed the cross and you observed 228 brown fish, 230 blue fish, 237 red fish, and 222 white fish in the F2 generation. Use a chi-square test to compare the observed and expected numbers of offspring. What conclusions can you draw from your statistical analysis of these results?

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