Estimate the harmonic mean of effective population size

How could rna viruses cause cancer
April 24, 2020
Solution-Surgical procedure such as this would lessen
April 24, 2020

Estimate the harmonic mean of effective population size

Question: The following effective population sizes were recorded for a population over 5 generations; 100, 120, 17, 40, 88. Estimate the harmonic mean estimate of effective population size for this population?
Question: Imagine you have two populations of size N = 4 and N = 20. Allele frequencies in each population are as follows; p =0.5 and q = 0.5. Use the binomial theorem to demonstrate why it is much more likely that fixation and loss of alleles will occur in the population of 4 than the population of 20.