A mutation in a gene disrupts paracrine signaling from a subset of cells in the pancreas. Which of the following mutant phenotypes is consistent with the information above?

A. A defect that affects functions all over the body
B. A defect affects only the pancreatic cells that are secreting the molecule
C. A defect affects cells in the pancreas other than the one’s secreting the molecule
D. A defect in the plasmodesmata
E. A defect that will increase muscle mass