Q1. 1. The FRP protein can function as either a positive regulator of transcription or as a negative regulator of transcription. FRP binds to its consensus sequence when fumarate is present. On the coding strand above, indicate where you would expect FRP to bind to the DNA. In one sentence, describe why the decision makes sense.

2. The NRR protein can function either as a positive regulator of transcription or as a negative regulator of transcription. NRR binds to its consensus sequence as nitrate is present. On the coding strand above, indicate where you would expect NRR to bind to the DNA. In one sentence, describe why the decision makes sense.

Q2. In recent years, there has been a concern of grade inflation within academia. Do you think a case might be made for performance appraisals being inflated? Why or why not? Research an article to support the opinion.