Carrying a mutation in one copy of the BRCA1 gene leads to increased risk of developing breast and/or ovarian cancer because as a woman ages, she risks mutating the other copy of the BRCA1 gene. Surprisingly, analysis of some cancers in BRCA1 carriers revealed one mutant copy and one normal […]

Biology: Week 2 – The molecules of life – macromolecule analogies This week you learned about the 4 types of biological macromolecules: lipids, carbohydrates, proteins and nucleic acids. In a nutshell, a macromolecule is a very large molecule consisting of many smaller structural units linked together (like how a train […]

Q. 1. Alleles might be explained as: a. similar forms of two different loci b. alike forms of two different genes c. Alternative forms of a single gene d. Alternative forms of two different loci 2. A mutation which produces a change from wild type to an abnormal phenotype is […]

Question: The OMIM description on “Genetic Mapping of Alkaptonuria” can be interpreted to say: The alkaptonuria gene was genetically mapped to 3q2 at 16cM away from the sucrase-isomaltast deficiency gene in inbred families with some members manifesting both conditions. Statistically the alkaptonuria causing mutant gene and the sucrase-isomaltase deficiency-causing mutant gene […]