Imagine a rabbit. A conejo. Its coat color is controlled by several loci, among them the C locus. C has several alleles; three of them are: C = full color (“chestnut agouti”), cch = chinchilla; c = albino. C is dominant to cch or c; cch is dominant to c; […]

Question 1How did the phrase “dumb jock” come to be? (This is a rhetorical question.) The phrase reflects two characteristics, intelligence and athletic prowess. Let us suppose that above average intelligence occurs in 25 out 100 children and superior athletic prowess occurs in 1 out 50 children. Using the rules […]

In a population of 50,000 diploid yeast cells (in this case the census and effective population sizes are identical) all cells have genotype A until a mutation (A-a) occurs, giving one copy of a. Alleles confer equivalent fitness. a. What is the probability that a will be fixed? b. How […]

Doll And Hill first evaluated the proposition that smoking was a risk factor for lung cancer in a case-control study (Doll and Hill, 1950). They determine that, of 650 men with lung cancer (cases), 645 had smoked at some time, in comparison with the 625 of the 650 men without […]