Q. Unlike the wild-type P0 protein, which is localized to the cell surface, the Ser63 deletion P0 mutant is exclusively located at the ER. Based on these observations, what is the most likely defect associated with the Ser63 deletion mutant? How would you design an experiment to test your hypothesis […]

Identical twins Jan and Fran were very close sisters. So when Jan died suddenly, Fran moved in to help take care of Jan’s daughter (her neice), Millie. Some time later Fran married her brother in law and became Millie’s stepmother. When Fran announced that she was pregnant, poor Millie became […]

Q1. A girl developed generalized seizures. A CT scan revealed a single brain lesion consistent with a tumour. Biopsy of the lesion showed a cysticercus. The patient lived in South Carolina and had never travelled outside the state. What parasite caused her disease? How is this disease transmitted? How might […]

In a test of his chromosome theory of heredity, Morgan crossed an (F1) female Drosophila with red eyes to a male with white eyes, cross (B). Morgan presumed the female was heterozygous for the X-linked recessive white-eye allele and that the male was hemizygous for white eye. The results of […]