1. Somatic hypermutation of antibody variable regions can occur during an immune response. It allows daughter cells to produce antibodies with a slightly different V region than the parent cell. Give one reason why this might be important for the efficacy of the antibody response. Explain why mutations of the […]

1. Cystic fibrosis is a chronic lung and digestive disease caused by a mutation in the CFTR gene on chromosome 7. In the United States approximately 39 in 10,000 individuals are affected with the recessive condition cystic fibrosis, 323 in 10,000 individuals are unaffected carriers, and 9,638 out of 10,000 […]

Q1. Imagine the allele controlling brown eyes B, is dominant over that controlling blue eyes b, in human beings. A blue eyed man marries the brown eyed woman and they have six children all brown eyed. What is most likely genotype of the father? Mother? If the seventh child had […]

Question: In yeast, one haploid strain is unable to synthesize uracil but able to synthesize leucine, while another haploid strain is able to synthesize uracil but not leucine. You think that the two genes occurring on different chromosomes permit synthesis of uracil and leucine. Your goal is todetermine if the two genes occur […]