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1. Provide a discussion of the normal anatomy of endochondral versus intramembranous bone growth. 2. Describe the pathological (disease) processes involved in achondroplasia, and answer this question: Why do individuals with achondroplasia have a normal sized head but abnormally proportioned limbs? 3. Discuss how bone remodels throughout life and the […]

Question: Diabetes and obesity are two metabolic diseases characterized by insulin resistance and a low-grade inflammation. Seeking an inflammatory factor causative of the onset of insulin resistance, obesity, and diabetes, we have identified bacterial lipopolysaccharide (LPS) as a triggering factor. We found that normal endotoxemia increased or decreased during the fed […]

Enzyme Kinetics with ?-glucosidase The lab report for the BM327 Biochemistry class will focus on Laboratory 3 (Enzyme assays with ?-glucosidase). Students will also be expected to apply knowledge from other laboratory sessions (Lab 1, Virtual Protein Purification; Lab 4, Functionality of Proteins) to outline a procedure for the purification of […]

Shown here are the amino acid sequences of the wild-type and three mutant forms of a short protein. Use this information to answer the following questions: Wild type: mer-trp-tyr-arg-gly-ser-pro-thrMutant 1: met-trpMutant 2: met-trp-his-arg-gly-ser-pro-thrMutant 3: met-cys-ile-val-val-val-gln-his Using Figure 13-7, predict the type of mutation that occurred leading to each altered protein.For […]