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Suppose that an enzyme uses a catalytic mechanism in which a functional group on the enzyme has to accept a proton from the intermediate formed in the first chemical step. The pKa of that basic functional group on the enzyme is 8.0, and is the only pKa apparent on a […]

Huntington disease is a fatal nervous system disorder causing degeneration of the brain.  It is caused by a defective gene on chromosome #4.  This is an autosomal dominant trait affecting 1 in 20,000 people. However, it is a delayed action gene that is not expressed until the affected individualis in […]

You are working for a neurological research center, and they need additional reading material for their waiting room. Create a 2- to 3-page illustrated brochure that includes the following: The anatomy of a neuron: Refer to the “Learning the External Parts of the Neuron” animation. A description of the neural […]

Q. A 50-year old man with the history of a duodenal ulcer is admitted to a hospital after several days of intermittent vomiting. On physical examination he is well-known to have orthostatic (when he stands up) changes in his blood pressure and pulse, no visible jugular venous distension, and marked […]