Question: In wild pigs, the allele for black fur (B) is dominant over the allele for brown (b) fur. A black wild pig is crossed with a brown wild pig, producing five F1 black wild pigs and six F1 brown wild pigs. a. (Assuming that no crossing over takes place) how […]

A 30 kg cocker spaniel is admitted to the hospital for exercise intolerance secondary to heart failure. You perform renal function measurements after infusing para-amino hippuric acid (PAH) and get the following values:Plasma creatine = 0.02 mg/ml (2mg/dl)Urinary creatine = 1.25 mg/mlUrinary volume = 30 ml urine in 60 minutesPlasma […]

1. How many total base pairs are in all the mammalian genes? 2. What proportion (%) of the total genome does this represent? 3. What is the probability that a random mutation will occur in any given gene? 4. Only 1 out of 3 mutations that occur in a gene […]

Q1. Drug effects are conditional. Drugs can target redundant gene products not limited to model systems Active compounds can help define drug leads and new “druggable” targets. Target identification can be technically challenging probably not as random as mutagenesis. What is essential for effective chemical genetics? Q2. Describe the term […]